Ryan ruled out as Ireland make four changes

Ireland: Osborne; Baloucoune, Ringrose, McCloskey, O'Brien; Crowley, Gibson-Park; O'Toole, Sheehan, Furlong, McCarthy, Beirne, Conan, Van der Flier, Doris (capt).

Replacements: Kelleher, Milne, Bealham, Murray, Timoney, Casey, Frawley, Aki.

Scotland: Kinghorn; Graham, Jones, Tuipulotu (capt), Steyn; Russell, White; Schoeman, Turner, Z Fagerson, Williamson, Gilchrist, M Fagerson, Darge, Dempsey.

Replacements: Ashman, Sutherland, Rae, Craig, Bradbury, Horne, Rowe, Jordan.